Mobilization of Renal and Hepatic Cadmium by Dithiocarbamates in Rats.

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Dithiocarbamates and cadmium metabolism: further correlations of cadmium chelate partition coefficients with pharmacologic activity.

N,N-bis(beta-Hydroxyethyl)dithiocarbamate (DHDC), N-methyl-N-hydroxyethyldithiocarbamate (MHDC), and N-ethyl-N-hydroxyethyldithiocarbamate (EHDC) were compared for their relative efficacies in promoting organ mobilization and excretion of metallothionein-bound cadmium (Cd). An attempt was made to correlate certain aspects of their pharmacodynamic properties with the octanol/aqueous partition co...

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ژورنال

عنوان ژورنال: Journal of Pharmacobio-Dynamics

سال: 1991

ISSN: 0386-846X,1881-1353

DOI: 10.1248/bpb1978.14.555